Bioinformatics Specialist - Protein Structure Prediction (AlphaFold / ESMFold) - Contract to Hire

Remote, USA Full-time Posted 2026-05-31
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We are looking for a Bioinformatics Specialist / Computational Biologist with deep expertise in AI-driven structural biology to assist with protein structure prediction and molecular modeling.

Project Scope:

The primary objective is to utilize AlphaFold (and/or similar state-of-the-art AI systems like ESMFold, RoseTTAFold) to predict, analyze, and model protein structures and molecular interactions relevant to our pipeline.

Key Responsibilities:

Run and configure AlphaFold/AlphaFold-Multimer pipelines for protein structure prediction.

Analyze and validate predicted models using pLDDT scores and PAE plots.

Perform molecular docking or interaction analysis between proteins and small molecules/ligands (if applicable).

Interpret computational data and translate it into actionable insights for chemistry/biology workflows.

Required Qualifications:

Proven experience working with AlphaFold, ESMFold, or Rosetta.

Strong background in Bioinformatics, Computational Biology, Biochemistry, or a related field (Ph.D. or Master’s preferred).

Proficiency in Python and handling biological data structures (PDB files, FASTA, etc.).

Experience with Linux environments, high-performance computing (HPC), or cloud-based GPU infrastructure (AWS, Google Cloud).

Ability to deliver clean, documented code and reproducible workflows.

How to Apply:

Please briefly describe your experience with AlphaFold in your proposal. Include a summary of a past project where you successfully modeled protein structures or molecular interactions using AI.

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